Source code of Demo page

<style>

:first-letter {
	font-size: 2em;
	padding-left: 1em;
}

div { margin: 0.5em 2em; border: 1px solid }

</style>

<h1>::first-letter</h1>

<div>
	test
</div>

<div>
	<div>
		test
	</div>
</div>

<div>
	<div>
		<div>
			test
		</div>
	</div>
</div>

Result in Chrome 20

Result in IE 10.0.8250.0